Phenotypes and Genotypes

Zusatztext

<p>Thistimely text presents a comprehensive guide to genetic association, a new andrapidly expanding field that aims to elucidate how our genetic code (genotypes)influences the traits we possess (phenotypes). The book provides a detailedreview of methods of gene mapping used in association with experimentalcrosses, as well as genome-wide association studies. Emphasis is placed onmodel selection procedures for analyzing data from large-scale genome scansbased on specifically designed modifications of the Bayesian informationcriterion. Features: presents a thorough introduction to the theoreticalbackground to studies of genetic association (both genetic and statistical); reviewsthe latest advances in the field; illustrates the properties of methods formapping quantitative trait loci using computer simulations and the analysis ofreal data; discusses open challenges; includes an extensive statisticalappendix as a reference for those who are not totally familiar with thefundamentals of statistics.<br></p>

Autorenportrait

<p><strong>Dr. Florian Frommlet</strong> is a researcher in the Center for Medical Statistics, Informatics, and Intelligent Systems at the Medical University of Vienna, Austria.</p><p><strong>Dr. Ma¿gorzata Bogdan</strong> is an Associate Professor in the Institute of Mathematics at Wroc¿aw University, Poland.</p><p><strong>Dr. David Ramsey</strong> is a Senior Lecturer in the Department of Operations Research at Wroc¿aw University of Technology, Poland.</p>

Weitere Details